A Mutant Rat with Congenital Skeletal Abnormalities and Polycystic Kidneys
نویسندگان
چکیده
منابع مشابه
Congenital abnormalities of bilateral kidneys.
A newborn infant was referred to the Department of Diagnostic Radiology, Princess Margaret Hospital, for further assessment for renal abnormalities detected by antenatal ultrasonography. Postnatal ultrasonography showed a cluster of noncommunicating cysts of varying sizes in the left renal fossa (Fig 1). The largest cyst was peripherally located. No normal renal parenchyma was detected in the l...
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Background & Aims: Chromosome abnormalities are a major cause of miscarriage and neonatal mortality. The present study aimed to determine the association of fetal and parents chromosomal abnormalities with congenital anomalies. Methods: A cross-sectional study was performed in a tertiary referral center (Afzalipour Hospital) over 16 months period (2011-2012). The study groups consisted of 77 fe...
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Erythropoietin (EPO) formation in kidneys of 18 patients with autosomal dominant polycystic kidney disease (ADPKD) was investigated. In 12 patients on hemodialysis and in 6 patients with preterminal renal failure serum, EPO was 29 +/- 7 and 16 +/- 1.5 mU/ml and hemoglobin concentrations were 11.0 +/- 0.6 and 12.7 +/- 1.2 g/dl, respectively. Cyst fluid from a total of 357 renal cysts was obtaine...
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BACKGROUND While the genetic basis of autosomal dominant polycystic kidney disease (ADPKD) has been clearly established, the pathogenesis of renal failure in ADPKD remains elusive. Cyst formation originates from proliferating renal tubular epithelial cells that de-differentiate. Fluid secretion with cyst expansion and reactive changes in the extracellular matrix composition combined with increa...
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ژورنال
عنوان ژورنال: Experimental Animals
سال: 1989
ISSN: 0007-5124,1881-7122
DOI: 10.1538/expanim1978.38.2_139